MODELING OF IONIZING RADIATION-INDUCED CHROMOSOME ABERRATION AND TUMOR PREVALENCE BASED ON TWO CLASSES OF DNA DOUBLE-STRAND BREAKS CLUSTERING IN CHROMATIN DOMAINS

There has been some controversy over the use of radiobiological models when modeling the dose-response curves of ionizing radiation (IR)-induced chromosome aberration and tumor prevalence, as those curves usually show obvious non-targeted effects (NTEs) at low doses of high linear energy transfer (LET) radiation.The lack of understanding the contri

Background Sexual selection and conflicts within and between sexes promote morphological diversity of reproductive traits within species.Variation in the morphology of diagnostic reproductive characters DANDRUFF/DRY SCALP CONDITIONER within species offer an excellent opportunity to study these evolutionary processes as drivers of species diversific

ABSTRACT RNA viruses replicate as complex mutant spectra termed viral quasispecies.The frequency of each individual genome in a mutant spectrum depends on its rate of generation and its relative fitness in the replicating population ensemble.The advent of deep sequencing methodologies allows for the first-time quantification of haplotype abundances